VITAMINS B1+B6+B12 Santa Maria

  • VITAMINS B1+B6+B12
  • VITAMINS B1+B6+B12

VITAMINS B1+B6+B12

NEUROBE
100 mg/100 mg/ 1 mg per 3 ml
Solution for Injection
(I.M./ I.V.)
Vitamins

Formulation:
Each 3 mL ampoule contains:
Thiamine hydrochloride (Vit.B1)………………. 100 mg
Pyridoxine hydrochloride (Vit.B6)……………. 100 mg
Cyanocobalamine (Vit.B12)……………………… 1 mg

With preservatives:
Benzyl Alcohol …………………………………………… 0.06 ml

Indications:
For the treatment of the diseases manifesting Vitamin B deficiency such as neuritis; alcohol toxic, and post infectious polyneuritis; diabetic polyneuropathy; neuralgia; sciatica; central spastic conditions, myasthenia; paresthesia; atherosclerosis; Wernicke’s encephalopathy; vegetative neurosis; dermatitis; neurodermatitis; psoriasis; lupus, erythematodes; furunculosis; stomatitis; cheilitis; glositis; colitis; hepatitis; chronic alcohol abuse; asthenia; anemia; intoxications.

Contraindications:
Vitamin B Complex should not be used in hypersensitivity to any of the vitamins, containing in the preparation, as well as in patients with 2-nd or 3-rd degree arterial hypertension.

Adverse effects:
Although the preparation is well tolerated, in rare cases in predisposed patients itching, urticaria, and Quincke’s edema may appear.

Drug Interactions:
The patient may reduce the antihypertensive effect of some adrenoreceptor blockers and andrenolytics, as well as to decrease the hypnotic effect of barbiturates and glutethimide, due to vitamin B1 persistence. Chlorpromazine increases in the urine excretion of the Vitamin B2. Probenecid inhibits tubular excretion and re absorption of the vitamin B2, reducing its excretion in urine. Vitamin B6 reduces the antiparkinsonic effect of L-Dopa. In concomitant treatment with oral contraceptive agents, isoniazid, penicillamine, cicloserin, and thiosemicarbazones the blood concentration of vitamin B6 is reduced.

Dosage and Administration:
Initial dose – 1 to 2 ampoules daily within 5 to 10 days.
Consequently 2 to 3 ampoules weekly for severe cases or as directed by the physician.

Precaution:
Because of in vitro incompatibility the preparation should not be used simultaneously (in the same syringe) with following preparations: Benzilpenicillin and oxacyllin (the antibiotic precipitates and is inactivated), macrolides (insoluble sedimentation is formed); Chloramphenicol (precipitation); Vitamin B12 (cobalt ions destruct vitamin B2) Vitamin C (inactivates vitamin B6)

Availability:
3ml amber glass ampoule USP type, box of 10 ampoules

Storage:
Store at room temperatures not exceeding 30C, protect from light. Do not freeze.

Caution:
Foods, Drugs, Devices and Cosmetics Act prohibit dispensing without prescription.

Warning:
This product contains Sodium Metabisulphite which may cause allergic type reactions including anaphylactic symptoms and life threatening or less reverse asthmatic episodes in certain susceptible persons.

*Do not use if precipitatoin/particale are visible which are due to unrecomended storage.
Manufactured by:
Harmann Pharmaceutical Lab (Pvt) Ltd
16 Km. Multan Road Lahore City Pakistan


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for cargo shipments (more than 1 kilo) 1-2 days
International shipments + shipment cost
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